Why the study?
Do calcium antagonists prevent alpha-adrenergic coronary constriction and myocardial ischemia in experimental dog models?
Do calcium antagonists prevent alpha-adrenergic coronary constriction and myocardial ischemia in experimental dog models?
Calcium antagonists functionally antagonize alpha-adrenergic coronary constriction, improving myocardial blood flow and reducing ischemia in experimental models.
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Supports calcium antagonist testing for sympathetic coronary constriction; leaves open translation from canine models to patients.
Heusch et al. (1991) studied this question.
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