What question did this study set out to answer?

To quantify the behavioral disturbances of frontotemporal dementia and compare them with behavioral changes observed in Alzheimer disease.

July 1, 1996Archives of Neurology

Alzheimer Disease and Frontotemporal Dementias

View Full Paper

Ask AI

Bookmark

To quantify the behavioral disturbances of frontotemporal dementia and compare them with behavioral changes observed in Alzheimer disease.
Cross-sectional comparison of 22 patients with frontotemporal dementia and 30 patients with Alzheimer disease matched for dementia severity.
Participants were recruited across two university-based outpatient clinics and a Veterans Affairs medical center, with diagnoses established using research diagnostic criteria and single photon emission computed tomography.
Behavioral disturbances were evaluated using the standardized Neuropsychiatric Inventory.
Patients with frontotemporal dementia had significantly higher total Neuropsychiatric Inventory scores than patients with Alzheimer disease, exhibiting more apathy, disinhibition, euphoria, and aberrant motor behavior.
A profile based on disinhibition, apathy, and depression correctly classified 77% of frontotemporal dementia patients and 77% of Alzheimer disease patients.
Patients with frontotemporal dementia presented higher levels of disinhibition and apathy accompanied by relatively lower levels of depression compared to patients with Alzheimer disease.

Authors

MLMorgan L. LevyWest Los Angeles College

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Cross-sectional study demonstrates distinct neuropsychiatric profiles in frontotemporal dementia compared to Alzheimer disease, indicating that behavioral patterns aid differential diagnosis.

Cite This Study

Morgan L. Levy (1996) studied this question.

synapsesocial.com/papers/6a1e9cdc44dc0a902547e2cd https://doi.org/10.1001/archneur.1996.00550070129021

View Full Paper

Ask AI

Bookmark

Implication

Cross-sectional study demonstrates distinct neuropsychiatric profiles in frontotemporal dementia compared to Alzheimer disease, indicating that behavioral patterns aid differential diagnosis.

Alzheimer Disease and Frontotemporal Dementias

Key Points

Discussion

Implication

Cite This Study

Alzheimer Disease and Frontotemporal Dementias

Key Points

Discussion

Implication

Cite This Study

Also Consider

Also Consider