Key result
Higher percussion entropy index is linked to ~9% lower diabetic peripheral neuropathy risk.
Why the study?
Diabetic peripheral neuropathy is a common neurological disorder in diabetic patients, prompting the development of a new percussion-based index to predict its occurrence using fingertip digital volume pulse signals.
Does higher PEIDVP predict a lower incidence of diabetic peripheral neuropathy in patients with type 2 diabetes?
Population
130 subjects (50 individuals without diabetes and 80 patients with type 2 diabetes)
Comparison
Risk factors and percussion entropy index (PEIDVP) in diabetic patients developing DPN vs not developing DPN
Authors
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Higher PEIDVP may aid DPN risk stratification in type 2 diabetes; leaves open incremental value and requires prospective validation.
Cohort (n=130)
Yes
Does higher PEIDVP predict a lower incidence of diabetic peripheral neuropathy in patients with type 2 diabetes?
Odds Ratio: 0.913 (95% CI 0.85–0.98)
p-value: p=0.017
PEIDVP derived from fingertip photoplethysmography may serve as a novel, non-invasive prognostic indicator for the development of diabetic peripheral neuropathy.
Wei et al. (2020) conducted a cohort in Type 2 diabetes (n=130). Percussion entropy index (PEIDVP) was evaluated on Incidence of diabetic peripheral neuropathy (DPN) within 5 years (OR 0.913, 95% CI 0.850-0.980, p=0.017). Higher percussion entropy index (PEIDVP) values were associated with a reduced risk of developing diabetic peripheral neuropathy within 5 years in patients with type 2 diabetes (OR 0.913).
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