Why the study?
Does a high-salt diet alter plasma and tissue levels of aldosterone and angiotensin II in male Dahl salt-sensitive rats?
Does a high-salt diet alter plasma and tissue levels of aldosterone and angiotensin II in male Dahl salt-sensitive rats?
High dietary salt induces inappropriate activation of local tissue renin-angiotensin-aldosterone systems, suggesting tissue levels may better reflect vascular maladaptations in hypertension.
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Local tissue RAAS activation by high salt may better reflect hypertensive maladaptations than plasma levels; hypothesis-generating, requires human validation.
Bayorh et al. (2005) studied this question.
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