Key result
Women taking low-dose combined oral contraceptives had a significantly higher triglycerides to high-density lipoprotein ratio compared to non-users (2.1 vs 1.1, p<0.01).
Why the study?
Combined oral contraceptive use is associated with increased cardiovascular risk markers such as lipid metabolism modifications, and small dense LDL particles are directly related to the triglycerides to HDL ratio.
Cross-Sectional (n=106)
Answers are grounded in this paper and cite their sources.
It is known that the combined oral contraceptive (COC) use has been associated with increase cardiovascular risk markers, such a lipid metabolism modifications. Small dense LDL particles (LDL phenotype B) are described as being more atherogenic than larger buoyant ones and its presence in bloodis directly related to triglycerides (TG) to high density lipoprotein (HDL) ratio.
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Santana do Sacramento (2020) conducted a cross-sectional in Healthy women (n=106). Low-dose combined oral contraceptives vs. No hormonal contraceptive was evaluated on Triglycerides to High Density Lipoprotein (TG/HDL) ratio (ES 1.5, p=<0.01). Women taking low-dose combined oral contraceptives had a significantly higher triglycerides to high-density lipoprotein ratio compared to non-users (2.1 vs 1.1, p<0.01).
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