Why the study?
While sugammadex instead of neostigmine may reduce postoperative pulmonary complications, whether this applies when sugammadex is given after neostigmine was unclear.
Does sugammadex as a rescue agent after neostigmine increase postoperative pulmonary complications compared to sugammadex alone in adult patients undergoing elective noncardiac surgery?
Population
1,672 adult elective inpatient noncardiac surgery patients receiving sugammadex for neuromuscular blockade reversal
Comparison
Sugammadex after neostigmine vs sugammadex alone
Design
Retrospective cohort study
Authors
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Rescue sugammadex after neostigmine was associated with more pulmonary complications; leaves open causality and need for randomized confirmation.
Does sugammadex as a rescue agent after neostigmine increase postoperative pulmonary complications compared to sugammadex alone in adult patients undergoing elective noncardiac surgery?
The use of sugammadex as a rescue agent after neostigmine failure is associated with a higher incidence of postoperative pulmonary complications compared to using sugammadex alone.
Bruceta et al. (2023) studied this question.
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