Key result
Coexisting hypertension and diabetes in Nigerian patients was associated with depressed systolic cardiac contractility (15% vs 23% in controls, p<0.01) and impaired exercise tolerance.
Population
56 Nigerian participants including 20 hypertensive-diabetic patients, 16 hypertensive patients, 10…
Design
Cross-sectional
Authors
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May prompt earlier cardiac evaluation in comorbid patients; hypothesis-generating and requires prospective studies before practice change.
Cross-Sectional (n=56)
Absolute Event Rate: 125% vs 111%
p-value: p=< 0.01
The coexistence of hypertension and diabetes in Nigerian patients synergistically worsens left ventricular systolic function, exercise capacity, and microvascular complications.
Babalola et al. (1992) conducted a cross-sectional in Hypertension associated with Diabetes Mellitus (n=56). Hypertension and diabetes mellitus vs. Healthy controls was evaluated on Left ventricular (LV) mass index (p=< 0.01). Coexisting hypertension and diabetes in Nigerian patients was associated with depressed systolic cardiac contractility (15% vs 23% in controls, p<0.01) and impaired exercise tolerance.
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