Key result
The autonomic system's modulation of the immune system is a novel and critical concept in understanding the pathogenesis and clinical outcomes of cardiovascular disease and hypertension.
Highlights the novel concept that autonomic neural regulation of the immune system influences the pathogenesis and clinical outcomes of cardiovascular disease and hypertension.
Neuroimmune pathways should not yet change hypertension management; leaves open their therapeutic targeting in future trials.
T he autonomic and the immune systems play major roles in the pathogenesis of cardiovascular disease and hypertension. To date, those 2 systems have been studied extensively but independently by cardiovascular biologists and by immunologists. The notion that the autonomic system can modulate the immune system and thereby influence the pathogenesis of cardiovascular disease and hypertension and their clinical outcome is novel and critical.
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Abboud et al. (2012) conducted a review in Cardiovascular disease and hypertension. Autonomic neural regulation of the immune system was evaluated. The autonomic system's modulation of the immune system is a novel and critical concept in understanding the pathogenesis and clinical outcomes of cardiovascular disease and hypertension.
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