LASCA with cross-correlation allows for high-resolution in vivo measurement of capillary microflow velocity beyond standard optical resolution limits.
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May advance preclinical microcirculation imaging; leaves open human validation for cardiovascular applications.
LASCA, combined with cross-correlation technique, has been applied for high-resolution measurements of the velocity of microflow and its structure in small blood capillaries in vivo. Such measurements have been carried out for the first time behind the resolution limit of the optical system.
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Ulyanov et al. (2008) studied this question.
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