What does this research mean for the field?

Cardiac energy metabolism and fuel selection flexibility are dynamically regulated at the transcriptional level by the nuclear receptor superfamily, specifically the PPAR/PGC-1alpha complex. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 16, 2004Circulation Research

Nuclear Receptor Signaling and Cardiac Energetics

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JHJanice M. HussWashington University in St. Louis

Daniel P. KellyGeneral Cardiology

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Implication

Potential metabolic targets in cardiac disease identified; leaves open clinical validation of PPAR/PGC-1 modulation.

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Cite This Study

Huss et al. (2004) studied this question.

synapsesocial.com/papers/6a1ed739ce3e167bb87e84f2 https://doi.org/10.1161/01.res.0000141774.29937.e3

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Heart failure HFrEF treatment

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Nuclear Receptor Signaling and Cardiac Energetics

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Cite This Study

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Nuclear Receptor Signaling and Cardiac Energetics

Discussion

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Implication

Key Points

Cite This Study

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