Key result
Cardiovascular magnetic resonance incorporating LGE had a diagnostic accuracy of 97%, equivalent to the 95% accuracy of invasive coronary angiography for determining heart failure etiology.
Why the study?
Does a CMR protocol incorporating LGE provide non-inferior diagnostic accuracy compared to invasive coronary angiography in determining the etiology of new-onset heart failure of uncertain etiology?
Cross-Sectional (n=120)
Does a CMR protocol incorporating LGE provide non-inferior diagnostic accuracy compared to invasive coronary angiography in determining the etiology of new-onset heart failure of uncertain etiology?
Absolute Event Rate: 97% vs 95%
LGE-CMR is a highly accurate, non-inferior, and potentially cost-effective noninvasive alternative to invasive coronary angiography for determining the etiology of new-onset heart failure.
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May support noninvasive LGE-CMR for new-onset HF etiology; leaves open prospective validation of noninferiority.
Assomull et al. (2011) conducted a cross-sectional in Heart failure of unknown etiology (n=120). Cardiovascular magnetic resonance (CMR) incorporating late gadolinium enhancement (LGE) vs. Invasive coronary angiography (CA) was evaluated on Diagnostic accuracy in determining the etiology of heart failure. Cardiovascular magnetic resonance incorporating LGE had a diagnostic accuracy of 97%, equivalent to the 95% accuracy of invasive coronary angiography for determining heart failure etiology.
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