Key result
Higher circulating triglycerides are linked to increased arterial stiffness in male firefighters.
Why the study?
Firefighters have an elevated CVD risk, making it vital to assess health areas needing improvement, such as the potential relationship between lipid metrics and arterial stiffness.
Is there a relationship between circulating lipids and arterial stiffness in male firefighters?
Cross-Sectional (n=20)
Is there a relationship between circulating lipids and arterial stiffness in male firefighters?
Higher triglyceride levels are associated with increased arterial stiffness in male firefighters, suggesting that managing triglycerides may be important for minimizing cardiovascular risk in this population.
Answers are grounded in this paper and cite their sources.
TG-PWV link in male firefighters is hypothesis-generating; leaves open causality and relevance to CV risk reduction.
Background/Objectives: Firefighters have an elevated risk of developing cardiovascular disease (CVD). Thus, it is vital to determine areas of health associated with the development of CVD that need improvement in the firefighter population, such as circulating lipids and arterial stiffness. The purpose of this study was to assess the potential relationship of lipid and lipoprotein metrics with measures of arterial stiffness in full-time firefighters in the southeastern United States. Methods: Twenty male full-time firefighters underwent a fasted blood draw to assess circulating lipids. Resting arterial stiffness was then assessed via pulse wave velocity (PWV) using an aortic measure. To determine the linear relationships between arterial stiffness and lipid measures of interest, a series of bivariate correlations were conducted as appropriate. The outcome variable was PWV measured continuously in m/s. The predictor variables were total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), small dense LDL-C (sdLDL-C), and triglycerides (TG) measured in mg/dL. All analyses were carried out using SPSS version 29 (α = 0.05). Results: TG levels were positively and moderately correlated with PWV (rs = 0.497, p = 0.026). No other significant relationships were detected between PWV and the remaining variables TC (rs = 0.104, p = 0.664), HDL-C (rs = −0.328, p = 0.158), LDL-C (rs = 0.184, p = 0.436), or sdLDL-C (rs = 0.330, p = 0.155). Conclusion: Higher TG levels are associated with higher PWV and thus, arterial stiffness. Management of circulating TG may be an important consideration in maximizing arterial health and minimizing CVD risk.
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Holland et al. (2025) conducted a cross-sectional in Arterial stiffness (n=20). Circulating lipids was evaluated on Pulse wave velocity (PWV) (rs = 0.497, p=0.026). Circulating triglyceride levels were positively correlated with pulse wave velocity (rs = 0.497, p = 0.026) in male firefighters, indicating an association with arterial stiffness.
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