Key result
Increasing evidence suggests an important connection between proinflammatory pathways, hyperinsulinemia, androgen excess, and adipose tissue dysfunction in polycystic ovary syndrome.
Population
Women of reproductive age with Polycystic Ovary Syndrome (PCOS)
Design
Review
Authors
Loading...
May inform cardiometabolic risk stratification in PCOS; leaves open targeted interventions pending prospective trials.
This review highlights the interplay between hyperandrogenaemia, insulin resistance, and adipocyte dysfunction in promoting a chronic low-grade inflammatory state and altered cardiometabolic profile in PCOS.
Dimitriadis et al. (2016) conducted a review in Polycystic Ovary Syndrome (PCOS). Adipokines and proinflammatory pathways was evaluated. Increasing evidence suggests an important connection between proinflammatory pathways, hyperinsulinemia, androgen excess, and adipose tissue dysfunction in polycystic ovary syndrome.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: