Key result
Self-navigated 3D T2 mapping enables accurate myocardial edema detection with ~41 ms baseline T2.
Why the study?
Does self-navigated isotropic 3D cardiac T2 mapping accurately quantify myocardial T2 and detect edema in healthy volunteers and patients?
Does self-navigated isotropic 3D cardiac T2 mapping accurately quantify myocardial T2 and detect edema in healthy volunteers and patients?
This novel self-navigated 3D T2 mapping technique enables accurate, isotropic whole-heart T2 quantification and edema detection without the need for respiratory navigators.
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May enable whole-heart edema assessment without navigators; extends 2D methods but leaves open clinical adoption pending larger validation.
Heeswijk et al. (2014) studied Healthy volunteers and patients with cardiovascular disease (n=13). Self-navigated isotropic 3D cardiac T2 mapping vs. 2D T2 mapping and spin-echo T2 mapping was evaluated on Average myocardial T2 in healthy volunteers. The self-navigated isotropic 3D cardiac T2 mapping technique allowed for accurate in vivo T2 quantification, demonstrating an average myocardial T2 of 40.5 ± 3.3 ms in healthy volunteers and detecting elevated T2 in patients with expected edema.
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