Key result
Compared to off-pump surgery, on-pump coronary artery bypass was associated with significantly higher median postoperative Troponin I levels at 6 hours (7.06 vs 1.86 ng/ml, p<0.001) and 12 hours.
Why the study?
The study was conducted to compare cardiac troponin-I levels during the postoperative period between on-pump and off-pump coronary artery bypass surgery.
Does on-pump coronary artery bypass surgery increase postoperative cardiac troponin-I levels compared to off-pump surgery in patients undergoing elective CABG?
Observational (n=100)
No
Does on-pump coronary artery bypass surgery increase postoperative cardiac troponin-I levels compared to off-pump surgery in patients undergoing elective CABG?
Absolute Event Rate: 7.06% vs 1.86%
p-value: p=<0.001
ONCAB is associated with higher early postoperative troponin-I release (at 6 and 12 hours) compared to OPCAB, though levels equalize by 18 to 24 hours.
Should not change CABG technique selection; leaves open whether early troponin differences affect clinical outcomes.
Objective: To compare cardiac troponin-I levels in post-operative period of on-pump (ONCAB) versus off-pump coronary artery bypass surgery. Study Design: Prospective Observational Study. Place and Duration of Study: Armed Forces Institute of Cardiology, from Jan 2019 to Dec 2019. Methodology: This prospective observational study was done at Armed Forces Institute of Cardiology from 1st January 2019 to 31st December 2019. Eighty six (43 in each on-pump and off-pump) patients admitted for elective coronary artery bypass grafting, aged 30-80 years were included in the study. Baseline data and cardiac troponin-I levels preoperatively as well as at 6, 12, 18 and 24 hours after the surgery in both groups were recorded and analyzed. Results: Out of 100 patients, mean age of the patients was 57.59 ± 10.24 years and 85% were males. All the base line characteristics, comorbid conditions and intra-operative findings were identical in both groups. There was marked rise in CK-MB levels postoperatively in overall participants. There was significant rise in Troponin I levels postoperatively in overall participants. Compared to OPCAB, postoperative Troponin I at 6hours and 12-hours was significantly higher in ONCAB. Conclusion: Compared to OPCAB, postoperative Troponin I at 6 hours and 12-hours was significantly high in ONCAB. However, there was no gross discrepancy in postoperative Troponin I levels between OPCAB and ONCAB at 18- & 24-hours after surgery.
No takes yet. Share an insight, caveat, or question.
Ullah et al. (2021) conducted an observational in Coronary artery disease requiring elective coronary artery bypass grafting (n=100). On-pump coronary artery bypass surgery (ONCAB) vs. Off-pump coronary artery bypass surgery (OPCAB) was evaluated on Postoperative Troponin I levels at 6 hours (ng/ml) (p=<0.001). Compared to off-pump surgery, on-pump coronary artery bypass was associated with significantly higher median postoperative Troponin I levels at 6 hours (7.06 vs 1.86 ng/ml, p<0.001) and 12 hours.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: