Key result
Conventional coronary artery bypass surgery was associated with significantly higher cardiac troponin I levels at 24 hours compared to off-pump surgery (5.51 vs 1.24 ng/ml; p<0.001).
Why the study?
Postoperative troponin elevation remains common after coronary artery bypass surgery despite technical advances, prompting evaluation of myocardial injury and associated factors with conventional versus off-pump approaches.
Does conventional coronary artery bypass graft compared to off-pump coronary artery bypass graft increase postoperative cardiac troponin I elevation in patients undergoing coronary artery bypass surgery?
Cohort (n=80)
No
Does conventional coronary artery bypass graft compared to off-pump coronary artery bypass graft increase postoperative cardiac troponin I elevation in patients undergoing coronary artery bypass surgery?
Absolute Event Rate: 5.51% vs 1.24%
p-value: p=< 0.001
Conventional CABG is associated with significantly higher postoperative myocardial injury, as measured by troponin I release, compared to off-pump CABG.
May indicate greater injury risk with conventional CABG; observational data leaves open effects on clinical outcomes.
Background: Although, advancements in techniques and perioperative management in coronary artery bypass surgery the elevation of postoperative troponin still occurs commonly. In this regard, we aimed to assess the degree of myocardial injury by measuring and comparing the levels of cardiac troponin I in the postoperative period of conventional versus off-pump coronary artery bypass graft and identify the most associated factors. Patients and methods: This prospective cohort study included the patients who underwent conventional coronary artery bypass surgery (46 patients) and off-pump coronary artery bypass surgery (34 patients), at Azadi heart Center in Duhok province during the period between 25th November 2021 and 25th May 2022. Results: The total amount of cardiac troponin release was significantly higher in the conventional than in the off-pump group. At one hour, the conventional means was 7.13 ng/ml while the off-pump was 1.56 ng/ml, p < 0.0001and at 24 hours, the convention mean was 5.51 ng/ml while the off-pump was 1.24 ng/ml, p < 0.001. The most associated factors in the conventional compared to the off-pump were advanced age, male gender, hypertension, renal impairment, Previous myocardial infarction, and timing of surgery. the main independent factors associated with cardiac troponin I elevation within 24 hours following conventional coronary artery bypass surgery were overweight, chronic renal failure, Smoking, and urgent procedure status. Conclusion: This study showed that the patients who underwent the conventional group had significantly higher levels of troponin I at 1 hour and 24 hrs, postoperatively. The higher postoperative troponin I among patients who underwent the conventional group was associated with being overweight, smoking, having chronic renal failure, and using urgent procedure status
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AHMED et al. (2023) conducted a cohort in Coronary artery bypass surgery (n=80). Conventional coronary artery bypass graft vs. Off-pump coronary artery bypass graft was evaluated on Cardiac troponin I level at 24 hours (ng/ml) (p=< 0.001). Conventional coronary artery bypass surgery was associated with significantly higher cardiac troponin I levels at 24 hours compared to off-pump surgery (5.51 vs 1.24 ng/ml; p<0.001).
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