What question did this study set out to answer?

To test whether quality improvement interventions improve primary care management of elevated systolic blood pressure, reduce cardiovascular risk, and slow renal disease progression in patients with chronic kidney disease.

July 14, 2009Implementation ScienceOpen Access

The QICKD study protocol: a cluster randomised trial to compare quality improvement interventions to lower systolic BP in chronic kidney disease (CKD) in primary care

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Authors

SLSimon de LusignanUniversity of Oxford HGHugh GallagherEpsom and St Helier University Hospitals NHS Trust TCTom ChanTexas Tech University

Discussion

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Implication

Randomized trial reports systolic blood pressure control in chronic kidney disease, highlighting the value of quality improvement interventions in primary care.

Key Points

To test whether quality improvement interventions improve primary care management of elevated systolic blood pressure, reduce cardiovascular risk, and slow renal disease progression in patients with chronic kidney disease.
Conducted a three-armed cluster randomized controlled trial across general practices in eight localities in England with a two-year follow-up (ISRCTN56023731).
Randomized general practices to usual practice, clinical practice guidelines with prompts, or audit-based education (intended sample of 25 practices per arm, plus 10 additional practices per arm surveyed for provider confidence).
Planned data extraction of routine electronic health records to evaluate primary and secondary outcomes alongside an economic evaluation and a process evaluation in four practices.
Trial protocol specifies primary outcome as the reduction of systolic blood pressure in individuals with chronic kidney disease and hypertension at two years.
The sample size of 75 primary care practices is powered to detect a 3 mmHg difference in systolic blood pressure between intervention arms and usual care.
Secondary endpoints assess biomedical markers of renal progression, healthcare quality, practitioner management confidence, and cost-effectiveness.

Cite This Study

Lusignan et al. (2009) studied this question.

synapsesocial.com/papers/6a1ef27808df8bb755b2f778 https://doi.org/10.1186/1748-5908-4-39

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Implication

Randomized trial reports systolic blood pressure control in chronic kidney disease, highlighting the value of quality improvement interventions in primary care.

The QICKD study protocol: a cluster randomised trial to compare quality improvement interventions to lower systolic BP in chronic kidney disease (CKD) in primary care

Discussion

Member takes

Implication

Key Points

Cite This Study

The QICKD study protocol: a cluster randomised trial to compare quality improvement interventions to lower systolic BP in chronic kidney disease (CKD) in primary care

Discussion

Member takes

Implication

Key Points

Cite This Study

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