Key result
A pharmacist-based multifactorial intervention did not significantly reduce systolic blood pressure compared to usual care in CKD patients with poorly controlled hypertension (135.1 vs 134.4 mmHg, p=0.57), though it improved guideline adherence.
Why the study?
Does a multifactorial pharmacist-based intervention improve blood pressure control and guideline adherence in primary care patients with moderate to severe CKD?
RCT (n=2,199)
Single-blind
Blocked and simple randomization
Yes
Does a multifactorial pharmacist-based intervention improve blood pressure control and guideline adherence in primary care patients with moderate to severe CKD?
Absolute Event Rate: 135.1% vs 134.4%
p-value: p=0.57
A pharmacist-based intervention in primary care CKD patients improved guideline adherence (PTH measurement) and antihypertensive prescribing, but did not significantly improve blood pressure control.
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Pharmacist intervention does not lower BP in CKD hypertension; extends evidence that it improves guideline adherence without affecting systolic pressure.
Cooney et al. (2015) conducted an RCT in Chronic kidney disease (CKD) (n=2,199). Pharmacist-based multifactorial intervention vs. Usual care was evaluated on Last clinic systolic blood pressure among participants with baseline BP >130/80 mmHg (p=0.57). A pharmacist-based multifactorial intervention did not significantly reduce systolic blood pressure compared to usual care in CKD patients with poorly controlled hypertension (135.1 vs 134.4 mmHg, p=0.57), though it improved guideline adherence.
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