Why the study?
Does adrenal medullectomy or bilateral renal artery denervation prevent the chronic episodic hypoxia-mediated increase in diurnal blood pressure in male Sprague-Dawley rats?
Does adrenal medullectomy or bilateral renal artery denervation prevent the chronic episodic hypoxia-mediated increase in diurnal blood pressure in male Sprague-Dawley rats?
The chronic episodic hypoxia-mediated increase in diurnal blood pressure requires both intact renal artery nerves and an intact adrenal medulla in a rat model.
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May implicate renal nerves and adrenal medulla in hypoxia-driven hypertension; leaves open translation to human sleep apnea.
Bao et al. (1997) studied this question.
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