Why the study?
Does hypoxemia alter splanchnic vasomotor responses and sympathetic nervous activity in humans at rest?
Population
Men (n=5 in Part I, n=5 in Part II, n=6 in Part III)
Comparison
Hypoxemia with or without intravenous… vs Breathing room air
Authors
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Preserved norepinephrine vasoconstriction during hypoxemia suggests no vasopressor adjustment; leaves open sympathetic-splanchnic mechanisms in clinical hypoxia.
Does hypoxemia alter splanchnic vasomotor responses and sympathetic nervous activity in humans at rest?
Severe hypoxemia causes mild splanchnic vasodilation without significantly increasing sympathetic nervous activity or preventing norepinephrine-induced vasoconstriction.
Rowell et al. (1986) studied this question.
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