Key result
Tissue Doppler imaging estimated a significantly higher peak left ventricular untwist rate during dobutamine stimulation compared to speckle tracking imaging (-112.1 vs -75.5 degrees/s; P<0.05).
Why the study?
Does tissue Doppler imaging provide different estimates of left ventricular untwist rate compared to speckle tracking imaging in a porcine model?
Does tissue Doppler imaging provide different estimates of left ventricular untwist rate compared to speckle tracking imaging in a porcine model?
Absolute Event Rate: -112.1% vs -75.5%
p-value: p=<0.05
Tissue Doppler imaging and speckle tracking imaging cannot be used interchangeably for measuring left ventricular untwist rate, as STI underestimates UR at high values.
Discordance between TDI and STI for LV untwist rate warrants caution in method selection; leaves open human validation studies.
AIMS: The study was designed to test the influence of the temporal resolution, at which tissue Doppler imaging (TDI) and speckle tracking imaging (STI) operate, on the accurate assessment of left ventricular (LV) untwist rate (UR). METHODS AND RESULTS: Echo imaging and invasive LV pressure measurements were performed during right atrial (RA) pacing and dobutamine challenge in eight pigs. LV torsion and torsional rate profiles were analysed from grey scale and tissue Doppler data (apical and basal short axis) at frame rates of 82 +/- 17 and 183 +/- 14 Hz, respectively. Temporal subsampling of TDI data sets was performed at 82 +/- 6 Hz in order to mimic the mean temporal resolution of STI and the LV torsional curves were again extracted. At rest, LV UR values were comparable for both imaging techniques. However, during dobutamine stimulation, TDI estimated peak UR was predominantly higher than UR measured by STI (-112.1 +/- 64.5 degrees /s vs. -75.5 +/- 31.4 degrees /s, P < 0.05). The similarity of LV UR measurements with respect to the STI/TDI data was examined by a Bland-Altman analysis. CONCLUSION: Although both methods regarding LV UR correlated well, these methods cannot be interchanged. STI showed a bias to underestimate UR at high values.
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Ferferieva et al. (2009) studied this question. Tissue Doppler imaging (TDI) vs. Speckle tracking imaging (STI) was evaluated on Peak left ventricular untwist rate during dobutamine stimulation (p=<0.05). Tissue Doppler imaging estimated a significantly higher peak left ventricular untwist rate during dobutamine stimulation compared to speckle tracking imaging (-112.1 vs -75.5 degrees/s; P<0.05).
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