Key result
This article is a methodological description of a randomized clinical trial evaluating combined training in hypertensive elderly; no clinical results are reported.
Why the study?
To evaluate the monthly time-course and associations between blood pressure changes and other health-related adaptations in response to exercise training in hypertensive elderly.
Does combined aerobic and resistance exercise training reduce blood pressure and improve other health-related adaptations in hypertensive elderly patients?
RCT
randomized
Does combined aerobic and resistance exercise training reduce blood pressure and improve other health-related adaptations in hypertensive elderly patients?
This protocol outlines a randomized clinical trial to evaluate the time-course of health-related adaptations, including blood pressure and immune/autonomic modulation, in response to combined exercise training in hypertensive elderly patients.
Does not alter practice without results; leaves open combined training effects on BP and adaptations in hypertensive elderly.
Aims: This article is a methodological description of a randomized clinical trial (ClinicalTrials.gov U1111-1181-4455) aiming to evaluate the time-course (monthly) and associations between blood pressure changes and other health-related adaptations in response to exercise training in hypertensive elderly. Methods: The patients will be randomized to a control or combined training group interventions (aerobic and resistance exercise), with monthly assessments in four months. Although, the changes in baseline blood pressure is the primary clinical outcome, the secondary outcomes include: body composition, cardiorespiratory fitness, muscle strength, arterial stiffness, baroreceptor sensitivity, cardiovascular autonomic modulation, inflammatory markers, oxidative stress, growth factors, tissue remodeling markers, metabolic profile, renal function, cognitive function and quality of life. Results: To support the understanding of the blood pressure changes in hypertensive elderly, a time-course of exercise-induced adaptations including cardiovascular and immunological adaptations are fundamental for research in this field. Conclusion: To investigate the time-course of combined training-induced adaptations including all the diverse aspects of health in hypertensive elderly a well-controlled protocol design is necessary, mainly to clarify the relationship between cardiovascular and immunological exercise-induced adaptations.
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Sardeli et al. (2018) conducted an RCT in hypertensive elderly. Combined training (aerobic and resistance exercise) vs. Control was evaluated on Changes in baseline blood pressure. This article is a methodological description of a randomized clinical trial evaluating combined training in hypertensive elderly; no clinical results are reported.
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