Key result
Older age was associated with delayed time to peak decrease in heart rate (3.8 vs 2.1 s) and mean blood pressure (8.3 vs 6.7 s) during carotid baroreceptor loading compared to young subjects (P<0.05).
Why the study?
Does ageing delay the peak cardiovascular response to acute carotid baroreceptor loading in humans?
Cross-Sectional
Does ageing delay the peak cardiovascular response to acute carotid baroreceptor loading in humans?
Absolute Event Rate: 3.8% vs 2.1%
p-value: p=< 0.05
Ageing is associated with delayed peak cardiovascular responses to acute carotid baroreceptor loading, which may be partly driven by age-related reductions in cardiac parasympathetic tone.
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May require age-adjusted baroreflex assessment in older adults; leaves open mechanisms and clinical relevance.
Fisher et al. (2009) reported a cross-sectional. Ageing vs. Young subjects was evaluated on Time to peak decrease in heart rate in response to neck suction (seconds) (p=< 0.05). Older age was associated with delayed time to peak decrease in heart rate (3.8 vs 2.1 s) and mean blood pressure (8.3 vs 6.7 s) during carotid baroreceptor loading compared to young subjects (P<0.05).
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