Key result
Heart rate fluctuations at the onset of light dynamic exercise are explained by rapid vagal withdrawal followed by a transient increase in vagal tone, which was abolished by atropine.
Why the study?
Does autonomic blockade alter heart rate fluctuations at the onset of muscular exercise in healthy males?
Population
6 healthy male subjects
Comparison
Parasympathetic blockade, beta-adrenergic… vs Control during the same exercise protocol
Design
Other
Follow-up
60-90 seconds
Authors
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May inform HR kinetics interpretation in exercise testing; leaves open translation beyond healthy males.
Does autonomic blockade alter heart rate fluctuations at the onset of muscular exercise in healthy males?
Heart rate fluctuations at the onset of light dynamic exercise are primarily driven by rapid vagal withdrawal followed by a transient increase in vagal tone.
Fagraeus et al. (1976) studied Healthy (n=6). Parasympathetic and beta-adrenergic blockade vs. Control was evaluated on Time courses of heart rate changes at the onset of muscular exercise. Heart rate fluctuations at the onset of light dynamic exercise are explained by rapid vagal withdrawal followed by a transient increase in vagal tone, which was abolished by atropine.
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