Why the study?
Does autonomic blockade with propranolol and atropine alter heart rate at rest and during exercise to determine vagal and sympathetic contributions in young healthy men?
Population
6 young healthy males
Comparison
0.4 mg/kg i.v. propranolol, 0.04 mg/kg i.v… vs Saline
Design
Other
Authors
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Highlights progressive sympathetic dominance with exercise in healthy young men; leaves open translation to disease states or therapies.
Does autonomic blockade with propranolol and atropine alter heart rate at rest and during exercise to determine vagal and sympathetic contributions in young healthy men?
This physiological study quantifies the progressive shift from parasympathetic to sympathetic dominance in heart rate control from rest to submaximal exercise.
G. Nyberg (1981) studied this question.
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