Key result
A family history of coronary artery disease significantly increased the odds of medication adherence (OR 2.06) in patients 6 months post-percutaneous coronary intervention, whereas 28% of the overall cohort remained non-adherent.
Cross-Sectional (n=269)
No
Odds Ratio: 2.06 (95% CI 1.15–3.67)
p-value: p=0.01
A significant proportion (28%) of post-PCI patients exhibit medication non-adherence, highlighting the need for cardiac rehabilitation programs to address psychosocial and familial factors.
May aid post-PCI adherence risk stratification via family history; hypothesis-generating and requires prospective validation before clinical use.
Introduction: Percutaneous Coronary Intervention (PCI) has no effect on coronary artery atherosclerosis, thus the modification of physiological risk factors seems essential to prevent coronary artery disease (CAD). Then PCI patients have to receive multiple drug therapies in an attempt to prevent the recurrence of cardiac events. In spite of the evidence based on medication adherence to prevent post-PCI CAD development, medication adherence is the main concern for health care system. Accordingly, this study aims to determine the medication adherence and its related factors among these patients. Methods: In this cross-sectional study, the statistical community was the patients undergoing PCI at medical educational hospital of Dr. Heshmat in Rasht, Iran. 269 patients were selected by convenient sampling method. The data were collected by a questionnaire consisting of 4 parts, namely the socio-individual factors, Morisky medication adherence scale, hospital anxiety and depression scale and cardiac patient’s self-efficacy scale. Data analysis was done by descriptive statistics and the significance variables in univariate analysis were examined in a multi logistic regression model through considering co-linearity. Results: The results showed that 75 patients (28%) didn’t adhere to the medication. In addition, the majority of them were reported to have clinical anxiety (44.2%) and mild depression (55.8%). Also, based on the results derived from multiple logistic regressions, only the spouse's educational level and family history of coronary artery disease were significant predictors of medication adherence. Conclusion: The current study findings display lack of complete post-PCI medication adherence, which underscores the importance of the existence of cardiac rehabilitation systems in the society. Therefore, it is recommended that cardiac rehabilitation centers be built in the society.
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Salari et al. (2018) conducted a cross-sectional in Coronary artery disease post-percutaneous coronary intervention (n=269). Family history of coronary artery disease vs. No family history of coronary artery disease was evaluated on Medication adherence (OR 2.06, 95% CI 1.15-3.67, p=0.01). A family history of coronary artery disease significantly increased the odds of medication adherence (OR 2.06) in patients 6 months post-percutaneous coronary intervention, whereas 28% of the overall cohort remained non-adherent.
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