Key result
Severe asymptomatic carotid disease during CABG is linked to similar postoperative stroke and death rates.
Why the study?
Although severe carotid artery disease is prevalent among patients undergoing CABG, clear management consensus is lacking, particularly for asymptomatic cases.
Does the presence of severe asymptomatic carotid artery disease increase the risk of in-hospital stroke and mortality in patients undergoing isolated CABG?
Cohort (n=235)
No
Does the presence of severe asymptomatic carotid artery disease increase the risk of in-hospital stroke and mortality in patients undergoing isolated CABG?
CABG in selected patients with severe asymptomatic carotid artery disease appears safe with similar short-term mortality and stroke rates compared to patients without severe carotid disease.
Supports CABG in selected patients with severe asymptomatic carotid disease; hypothesis-generating and requires prospective validation.
Background: Although the prevalence of severe carotid artery disease (CAD) in patients undergoing coronary artery bypass grafting (CABG) is high, no clear consensus on how to manage these patients exists, especially in asymptomatic cases. We aimed to determine the impact of asymptomatic severe CAD on in-hospital stroke and all-cause mortality rates in patients undergoing CABG. Methods: We retrospectively analyzed 235 patients with documented carotid duplex ultrasound before undergoing isolated CABG at our institution between August 2015 and December 2022. To assess the rates of stroke and mortality after CABG, patients with severe CAD were compared with those without. Staged or concomitant carotid revascularization was considered in patients with severe bilateral CAD or a poor collateral brain network. Results: Patients with severe CAD were significantly older with a higher prevalence of CAD treatment history. Although their intensive care unit stay was longer, other postoperative complications were not significant. Among all patients, only one occurrence of 30-day mortality was observed, and patients with severe CAD had similar rates of postoperative stroke and death to those without. Postoperative stroke was related to carotid artery lesions in 2 patients with severe CAD but not in 9 patients without. Carotid artery stenting (CAS) was successfully performed without cerebral complications. Conclusions: Coronary artery bypass grafting in selected patients with severe asymptomatic CAD is acceptable and favorable; however, stroke related to severe CAD can occur after CABG. The decision to perform prophylactic or subsequent revascularization must be personalized and based on clinical judgment; however, close follow-up is required for patients with severe asymptomatic CAD. Furthermore, to prevent perioperative cerebrovascular events, preoperative carotid evaluation with a duplex ultrasonography scanner appears important.
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Sugiyama et al. (2024) conducted a cohort in Severe asymptomatic carotid artery stenosis in patients undergoing CABG (n=235). Severe asymptomatic carotid artery disease vs. No severe carotid artery disease was evaluated on In-hospital stroke and all-cause mortality. Severe asymptomatic carotid artery disease in patients undergoing CABG was associated with similar rates of postoperative stroke and death compared to patients without severe disease.
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