A study on high level aminoglycoside resistant enterococci isolated from urinary tract infection

Enterococci infection have been treated with cell wall active aminoglycoside as the synergic effect overcomes the intrinsic resistance exhibited by Enterococci. High level aminoglycoside resistance leads to synergy resistance and treatment failure.The present study was conducted to determine the prevalence of high level aminoglycoside resistance among isolates of enterococci from urine sampleA Enterococci isolates were included in this study. High Level Aminoglycoside Resistance (HLAR) was determined by agar dilution method and E test. Of the were Enterococcus faecalis, 14.29% were Enterococcus Enterococcus avium. 60(40.82%) were found to be resistant to Amp High LeveGentamicin (HLG), 24(16.33%) to Nitrofurantoin of 120 E.faecalis isolates, 39(32.50%) were resistant to Ampicillin and 57(47.50%) to High Level Gentamicin.Among the E.faecium isolates studied, Ampicillin, 12(57.14%) to High Level Gentamicin. High level 2000g/ml) was seen in 22.45 % isolates by agar dilution method E.faecalis isolates and 71.43% E.faecium were with a Minimum Inhibitory Concentration(MIC) of 1024g/ml of Gentamicin.Monitoring of should be carried out by high content aminoglycoside disk and agar screen method.