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May 6, 2015Expert Review of Cardiovascular Therapy

Risk stratification for sudden death in arrhythmogenic right ventricular cardiomyopathy

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Key result

This review appraises available evidence for risk stratification in arrhythmogenic right ventricular cardiomyopathy to guide primary prevention implantable cardioverter-defibrillator therapy.

Why the study?

Does implantable cardioverter-defibrillator (ICD) therapy prevent sudden cardiac death in patients with arrhythmogenic right ventricular cardiomyopathy?

Population

Patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC)

Design

Review

Authors

JCJulia Cadrin‐TourignyElectrophysiologyRTRafik TadrosElectrophysiologyMTMario TalajicElectrophysiology

Discussion

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Member takes

Overview

Current risk stratification warrants caution for primary prevention ICD decisions in ARVC; leaves open need for validated predictors.

Structured PICO

Does implantable cardioverter-defibrillator (ICD) therapy prevent sudden cardiac death in patients with arrhythmogenic right ventricular cardiomyopathy?

P
Population
Patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC)
I
Intervention
Implantable cardioverter-defibrillator (ICD) therapy
O
Outcome
Sudden cardiac deathhard clinical

This review provides evidence-based guidance on risk stratification for sudden cardiac death in ARVC to inform decisions regarding primary prevention ICD therapy.

Cite This Study

Cadrin‐Tourigny et al. (2015) conducted a review in Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC). Implantable cardioverter-defibrillator (ICD) therapy and risk stratification was evaluated on Sudden cardiac death. This review appraises available evidence for risk stratification in arrhythmogenic right ventricular cardiomyopathy to guide primary prevention implantable cardioverter-defibrillator therapy.

synapsesocial.com/papers/6a1f39fbc333d7dc9c232e79https://doi.org/10.1586/14779072.2015.1043891
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Follow-up by repeated signal-averaged surface QRS in patients with the syndrome of arrhythmogenic right ventricular dysplasia1989 · 29 citations
  2. 2Prospective Randomized Multicenter Trial of Empirical Antitachycardia Pacing Versus Shocks for Spontaneous Rapid Ventricular Tachycardia in Patients With Implantable Cardioverter-Defibrillators2004 · 776 citations
  3. 3Arrhythmogenic Right Ventricular Cardiomyopathy 2012: Diagnostic Challenges and Treatment2012 · 36 citations
  4. 4Prognostic Value of Endocardial Voltage Mapping in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia2013 · 108 citations
  5. 5Outcomes of Catheter Ablation of Ventricular Tachycardia in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy2012 · 198 citations