Key result
PCI links to improved physical quality of life through 6 months in men with ACS.
Why the study?
Health-related quality of life among ACS survivors had not been extensively studied following cardiac management.
Does percutaneous coronary intervention (PCI) improve quality of life in male patients with a first episode of acute coronary syndrome?
Cohort (n=145)
No
Does percutaneous coronary intervention (PCI) improve quality of life in male patients with a first episode of acute coronary syndrome?
p-value: p=0.011
In male survivors of a first acute coronary syndrome episode, successful revascularization with PCI is associated with significant improvements in the physical domain of quality of life over 6 months.
Associated with physical QoL gains post-PCI in male first-ACS patients; hypothesis-generating and requires randomized confirmation before practice change.
Background: Assessment of health-related quality of life (HRQoL) is an important measure of a patient's recovery after an illness. However, HRQoL among acute coronary syndrome (ACS) survivors has not been extensively studied following cardiac management. Aim: The purpose of this study was to assess the quality of life (QoL) among ACS patients who have undergone percutaneous coronary intervention (PCI). Methods: This cohort study included 145 consecutive male ACS patients between March 2021 and May 2022. Of these patients, 138 (mean age 54.3 ± 10.7 years) completed the QoL assessment using the short form-12 (SF-12) health survey questionnaire. Seventy (51%) of them presented with ST-segment elevation myocardial infarction (STEMI), 18 (13%) had non-STEMI, 39 (28%) had evolved MI, and 11 (8%) had unstable angina. Recruited patients' QoL data were assessed at various time points post-PCI. Results: At the end of the 12 months of follow-up, major clinical events (MCE) defined as death, sudden death, or re-acute myocardial infarction occurred in 54.9% of patients. Out of 7 MCE, four deaths and three re-AMIs had occurred. SF-12 physical component score was found to be significantly improved when compared to the mental component score, which seems to improve without reaching statistical significance over time. Among event-free ACS patients, we found a significant positive correlation between left ventricular ejection fraction and HRQoL. Conclusion: Improvement in HRQoL (physical component) was seen among ACS patients post-PCI. Relevance for Patients: QoL assessment outcomes should be considered in clinical settings, practice guidelines, and treatment modality post-PCI to improve QoL in post-ACS survivors.
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Seetharam et al. (2023) conducted a cohort in Acute coronary syndrome (ACS) (n=145). Percutaneous coronary intervention (PCI) was evaluated on SF-12 physical component score (PCS-12) over 6 months (p=0.011). Among male patients with a first episode of acute coronary syndrome, the physical component of quality of life significantly improved from 1 to 6 months post-PCI (p=0.011).
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