Key result
Invasive coronary revascularization with PCI or CABG in octogenarian patients was associated with relatively high in-hospital mortality but yielded acceptable long-term survival (>60% at 5 years) and satisfactory quality of life among survivors.
Why the study?
Does invasive coronary revascularization (PCI or CABG) provide acceptable survival and quality of life in octogenarian patients with ischemic coronary disease?
Cohort (n=164)
No
Does invasive coronary revascularization (PCI or CABG) provide acceptable survival and quality of life in octogenarian patients with ischemic coronary disease?
Absolute Event Rate: 21.6% vs 14.3%
p-value: p=NS
Invasive coronary revascularization in octogenarians carries a high in-hospital mortality risk but yields acceptable long-term survival and satisfactory quality of life for those who survive to discharge.
Supports individualized revascularization decisions in selected octogenarians; leaves open need for randomized trials to guide selection.
BACKGROUND: Thus far, the outcome and effect of percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery on the quality of life of octogenarian patients has not been accurately assessed in Japan. METHODS AND RESULTS: A retrospective analysis of the outcome of invasive coronary revascularization in 130 elderly patients (age, > or =80 years) with ischemic coronary disease was carried out. Their current quality of life was determined by the Seattle Angina Questionnaire. Although the in-hospital death rate was relatively high (21.6% after PCI and 14.3% after CABG surgery), the long-term outcome of the patients who did not die during the in-hospital period after the PCI/CABG surgery was acceptable (5-year survival rate, >60%). All domains of the questionnaire received a favorable score from a majority of the survivors, irrespective of the treatment they received. CONCLUSIONS: The quality of life and longevity of the octogenarian patients following extensive invasive revascularization for ischemic coronary artery disease were satisfactory.
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Kamiya et al. (2007) conducted a cohort in Ischemic heart disease (n=164). Percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) vs. Medical treatment was evaluated on In-hospital mortality (p=NS). Invasive coronary revascularization with PCI or CABG in octogenarian patients was associated with relatively high in-hospital mortality but yielded acceptable long-term survival (>60% at 5 years) and satisfactory quality of life among survivors.
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