Key result
Distinct molecular entities underlie the various electrophysiologically distinct repolarizing voltage-gated K+ currents in mammalian myocardial cells.
Population
Mammalian myocardium / cardiac cells
Design
Review
Authors
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Guides molecular targeting of cardiac repolarizing currents; leaves open clinical translation pending human validation.
This review outlines the molecular basis and subunit composition of diverse voltage-gated potassium channels responsible for repolarizing currents in the mammalian heart.
Jeanne M. Nerbonne (2000) conducted a review in Voltage-gated K+ channel diversity in mammalian myocardium. Distinct molecular entities underlie the various electrophysiologically distinct repolarizing voltage-gated K+ currents in mammalian myocardial cells.
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