Why the study?
Does CO2 rebreathing reveal abnormal chemoreceptor sensitivity in medication-free patients with agoraphobia and panic attacks compared to healthy subjects?
Population
n=37 total; 14 medication-free patients with agoraphobia and panic attacks, and 23 healthy subjects.
Comparison
CO2 rebreathing technique to measure ventilatory… vs Healthy subjects matched for age, sex, and…
Design
Case-control
Authors
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No difference in CO2 chemosensitivity in panic disorder; leaves open alternative mechanisms for CO2-induced anxiety.
Does CO2 rebreathing reveal abnormal chemoreceptor sensitivity in medication-free patients with agoraphobia and panic attacks compared to healthy subjects?
Panic anxiety patients do not have abnormally high central medullary chemoreceptor sensitivity to CO2 compared to healthy controls, despite experiencing greater anxiety during CO2 rebreathing.
Scott W. Woods (1986) studied this question.
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