What is the clinical evidence from this study?

Study design: Case Report. Population: Wolff-Parkinson-White syndrome with reciprocating atrioventricular tachycardia (n=2). Intervention: Dual-demand pacemaker. Primary outcome: Termination of tachycardia attacks.

What question did this study set out to answer?

To evaluate whether a modified demand pacemaker that automatically switches to fixed-rate pacing during tachycardia can terminate reciprocating atrioventricular tachycardia in patients with Wolff-Parkinson-White syndrome.

May 8, 1976BMJOpen Access

Dual-demand pacing for reciprocating atrioventricular tachycardia.

Q: What does this research mean for the field?

An implantable demand pacemaker modified to automatically switch into fixed-rate pacing upon tachycardia detection consistently terminates intractable reciprocating atrioventricular tachycardia in patients with Wolff-Parkinson-White syndrome. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

Modified dual-demand pacing consistently terminates intractable reciprocating AV tachycardia in WPW syndrome.

Why the study?

Does a dual-demand pacemaker terminate reciprocating atrioventricular tachycardia in patients with Wolff-Parkinson-White syndrome?

Population

2 patients with Wolff-Parkinson-White syndrome and intractable reciprocating atrioventricular tachycardia.

Design

Case_report

Follow-up

18 months (for Case 1)

Authors

DKD M KriklerUniversity of Ulster PCP V CurryUniversity of London JBJorge BuffetUniversidad Francisco de Vitoria

Discussion

Member takes

Implication

Supports dual-demand pacing feasibility in WPW with intractable AVRT; leaves open need for controlled trials before clinical adoption.

Key Points

To evaluate whether a modified demand pacemaker that automatically switches to fixed-rate pacing during tachycardia can terminate reciprocating atrioventricular tachycardia in patients with Wolff-Parkinson-White syndrome.
Studied the initiation and termination of reciprocating atrioventricular tachycardia using programmed electrical stimulation of the heart in 2 patients with Wolff-Parkinson-White syndrome.
Implanted a modified demand pacemaker in each patient programmed to automatically switch to fixed-rate pacing (70 beats/min in Case 1) whenever tachycardia began or bradycardia occurred.
Programmed electrical stimulation demonstrated that induced tachycardias responded rapidly and consistently to fixed-rate pacing.
Automatic activation of the implanted pacemaker successfully terminated tachycardia episodes rapidly (within 30 seconds for induced attacks in Case 1).
Both patients experienced successful control of otherwise intractable paroxysmal tachycardia.

Study Design

Type

Case Report (n=2)

Structured PICO

Does a dual-demand pacemaker terminate reciprocating atrioventricular tachycardia in patients with Wolff-Parkinson-White syndrome?

Population

2 patients (aged 44 and 64, 1 female) with Wolff-Parkinson-White syndrome and intractable reciprocating atrioventricular tachycardia.

Intervention

Implantation of a dual-demand pacemaker modified to switch to fixed-rate pacing (e.g., 70 beats/min) when tachycardia begins.

Outcome

Termination of tachycardia attacks

Dual-demand pacing is a promising and effective treatment for terminating intractable reciprocating atrioventricular tachycardia in selected patients with Wolff-Parkinson-White syndrome.

Cite This Study

Krikler et al. (1976) conducted a case report in Wolff-Parkinson-White syndrome with reciprocating atrioventricular tachycardia (n=2). Dual-demand pacemaker was evaluated on Termination of tachycardia attacks. A modified dual-demand pacemaker successfully and consistently terminated attacks of intractable reciprocating atrioventricular tachycardia in two patients with Wolff-Parkinson-White syndrome.

synapsesocial.com/papers/6a1f446f1c1c5348ad2aa62e https://doi.org/10.1136/bmj.1.6018.1114

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Dual-demand pacing for reciprocating atrioventricular tachycardia.

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Dual-demand pacing for reciprocating atrioventricular tachycardia.

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

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