Key result
Percutaneous SVC stenting improves symptoms and cardiac output in a lipomatous hypertrophy obstruction case.
Why the study?
Lipomatous hypertrophy of the interatrial septum is usually asymptomatic but may rarely lead to hemodynamic compromise.
Does percutaneous SVC stenting relieve symptoms and improve hemodynamics in a patient with SVC obstruction due to lipomatous hypertrophy of the interatrial septum?
Case Report (n=1)
Does percutaneous SVC stenting relieve symptoms and improve hemodynamics in a patient with SVC obstruction due to lipomatous hypertrophy of the interatrial septum?
Answers are grounded in this paper and cite their sources.
Percutaneous SVC stenting can serve as a safe, effective, and minimally invasive alternative to surgery for relieving venous obstruction caused by lipomatous hypertrophy of the interatrial septum in high-risk patients.
BACKGROUND: Lipomatous hypertrophy of the interatrial septum (LHIS) is a benign cardiac tumor involving nonencapsulated fat. While usually asymptomatic, it may rarely lead to hemodynamic compromise. CASE SUMMARY: An 83-year-old man with ischemic cardiomyopathy presented with worsening dyspnea. Evaluation revealed in-stent restenosis of the right coronary artery, which was treated percutaneously. Symptoms persisted, prompting cardiac magnetic resonance, which identified LHIS causing obstruction of ≥50% of the superior vena cava (SVC). Given favorable anatomy, percutaneous SVC stenting was performed. At 6-month follow-up, the patient was symptom-free with improved cardiac output. DISCUSSION: Although LHIS is typically benign, it can cause significant venous obstruction. This case highlights the value of multimodality imaging and introduces percutaneous stenting as a minimally invasive alternative to surgery in selected patients. TAKE-HOME MESSAGES: Multimodality imaging is key in LHIS diagnosis. Percutaneous SVC stenting can be a safe, effective option in high-risk patients.
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Milutinovic et al. (2025) conducted a case report in Lipomatous hypertrophy of the interatrial septum causing superior vena cava obstruction (n=1). Percutaneous superior vena cava stenting was evaluated on Symptom relief and cardiac output improvement. Percutaneous superior vena cava stenting successfully relieved symptoms and improved cardiac output at 6 months in an 83-year-old man with obstruction due to lipomatous hypertrophy.
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