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This review summarizes decades of clinical trial evidence that forms the foundation of current guideline-directed management for acute coronary syndromes.
In managing acute coronary syndromes, physicians can draw on a large body of evidence from clinical trials. This article reviews clinical trials that inform current standards of practice regarding reperfusion, aggressive vs conservative initial approaches, and the appropriate use of aspirin, dual antiplatelet therapy, glycoprotein IIb/IIIa antagonists, anticoagulants, and statins.
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A. Michael Lincoff (2014) studied this question.
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