Why the study?
Does pyruvate augment calcium transients and cell shortening in isolated rat ventricular myocytes?
Does pyruvate augment calcium transients and cell shortening in isolated rat ventricular myocytes?
Pyruvate acts as a metabolic inotrope by augmenting intracellular calcium transients and cell shortening in ventricular myocytes.
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Supports pyruvate as metabolic inotrope in rat myocytes; leaves open translation to human HF therapy.
Martin et al. (1998) studied this question.
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