Key result
A review of evidence indicates a frequent positive correlation between renin substrate concentration and elevated blood pressure, suggesting it may be a causal factor in hypertension.
Why the study?
Is increased renin substrate concentration a causal factor in hypertension?
Is increased renin substrate concentration a causal factor in hypertension?
This review highlights a positive correlation between renin substrate concentration and blood pressure, suggesting a potential causal role in hypertension.
Should not change hypertension management; leaves open a causal role for renin substrate pending prospective trials.
A positive correlation between blood pressure and renin substrate concentration is found in a wide variety of conditions in human beings and in animal experiments. The evidence concerning this relationship is reviewed and the exceptions are discussed. The frequent positive correlation between renin substrate and elevated blood pressure suggests that increased renin substrate concentration may be a causal factor in hypertension.
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David B. Gordon (1983) conducted a review in Hypertension. Renin substrate concentration was evaluated on Blood pressure. A review of evidence indicates a frequent positive correlation between renin substrate concentration and elevated blood pressure, suggesting it may be a causal factor in hypertension.
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