Why the study?
Does oral diltiazem reduce the frequency of anginal attacks at rest in patients with angina pectoris?
Does oral diltiazem reduce the frequency of anginal attacks at rest in patients with angina pectoris?
Oral diltiazem is effective for variant angina with ST elevation but insufficient for angina with ST depression.
Supports selective diltiazem use in ST-elevation variant angina; leaves open benefit in ST-depression rest angina.
The effect of oral administration of diltiazem, a new 1,5-benzothiazepine derivative, on the frequency of anginal attack at rest was studied in 8 patients. Our own experience showed that diltiazem gave excellent results in patients with ST elevation (variant type) but its effect was insufficient in the patients whose ST segment was depressed during the attack.
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Nakamura et al. (1979) studied this question.
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