What question did this study set out to answer?

Evaluate how insecticide resistance develops in mosquito populations and explore methods to inhibit this resistance.

Selection for and against insecticide resistance and possible methods of inhibiting the evolution of resistance in mosquitoes

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Randomized trial assesses methods to inhibit insecticide resistance evolution in mosquitoes, suggesting new strategies for pest control.

Evaluate how insecticide resistance develops in mosquito populations and explore methods to inhibit this resistance.
Analyzed published data on insecticide resistance rates in Anopheles culicifacies and An. stephensi.
Calculated coefficients of selection for dominant, recessive and intermediate resistance mechanisms.
Assessed the impact of alternate insecticide spraying and releasing susceptible males on resistance evolution.
DDT resistance in An. culicifacies showed a fitness advantage of resistant individuals of 1.28–1.51 times that of susceptibles.
Coefficients of selection against resistance were inversely related to the initial frequency of susceptibility genes.
Implementing a grid system along with periodic releases of susceptible males can significantly reduce resistance evolution rates.

Curtis et al. (1978) studied this question.

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