Key result
Genetic influences accounted for 60% to 100% of the phenotypic tracking correlations in blood pressure and hemodynamics between ages 14 and 18, with novel genetic effects explaining 17% to 33% of variance at follow-up.
Why the study?
What are the relative contributions of genetic and environmental factors to the stability of blood pressure and hemodynamics between ages 14 and 18 years in European American and African American twins?
Observational
What are the relative contributions of genetic and environmental factors to the stability of blood pressure and hemodynamics between ages 14 and 18 years in European American and African American twins?
Novel genetic effects emerge during adolescence that explain a considerable part of the variation in blood pressure and hemodynamics, while environmental influences become more important with age in African Americans compared with European Americans.
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Adolescent BP tracking appears largely genetic; leaves open ancestry-specific interventions pending prospective validation.
Kupper et al. (2006) conducted an observational in Blood pressure and hemodynamics. Genetic and environmental factors was evaluated on Stability of blood pressure and underlying hemodynamic characteristics. Genetic influences accounted for 60% to 100% of the phenotypic tracking correlations in blood pressure and hemodynamics between ages 14 and 18, with novel genetic effects explaining 17% to 33% of variance at follow-up.
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