Experimental findings demonstrate efficient enamide synthesis in a cascade reaction using enaminones and cyclopropenones, highlighting its synthetic utility.
Herein, we report an addition‐elimination ring opening reaction cascade between cyclopropenones and enaminones with Ag(I) catalysis. The successful utilization of enaminones as the carbon nucleophiles enables the practical synthesis of enamides via ring opening. In addition, the two‐step operation by subjecting the in situ generated enamides to oxidative conditions allows the synthesis of oxazoles featuring a C2‐vinyl substituent by CO bond construction.
No takes yet. Share an insight, caveat, or question.
Wen et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: