Strain-induced PtCu nanozymes for paper-based portable colorimetric immunoassay of carcinoembryonic antigen with smartphone readout

Qingliang Lin; Yibin Zeng; Zhichao Yu; Dianping Tang; Xuejing Wu

doi:10.1039/d6ay00867d

January 1, 2026Analytical Methods

Strain-induced PtCu nanozymes for paper-based portable colorimetric immunoassay of carcinoembryonic antigen with smartphone readout

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Key Points

The aim is to develop a portable colorimetric immunoassay for carcinoembryonic antigen (CEA) using highly active PtCu nanozymes for better cancer detection.
Constructed PtCu bimetallic nanozymes for the assay.
Developed a paper-based immunoassay format.
Utilized smartphone technology for result readout.
Achieved rapid and accurate detection of CEA with high sensitivity.
Demonstrated successful correlation between color change and CEA concentration.
Portable device showed feasibility for early cancer screening.

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Implication

Demonstrates rapid detection of carcinoembryonic antigen using portable nanozymes, implying improved cancer screening methods.

Abstract

Rapid and accurate detection of carcinoembryonic antigen (CEA) is of significant clinical importance for early cancer screening and prognosis monitoring. In this study, highly active PtCu bimetallic nanozymes were constructed...

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Cite This Study

Lin et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc64adee9eb8c0dce7778 https://doi.org/10.1039/d6ay00867d

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Strain-induced PtCu nanozymes for paper-based portable colorimetric immunoassay of carcinoembryonic antigen with smartphone readout

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Strain-induced PtCu nanozymes for paper-based portable colorimetric immunoassay of carcinoembryonic antigen with smartphone readout

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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