Strain-induced PtCu nanozymes for paper-based portable colorimetric immunoassay of carcinoembryonic antigen with smartphone readout

Key Points

• The aim is to develop a portable colorimetric immunoassay for carcinoembryonic antigen (CEA) using highly active PtCu nanozymes for better cancer detection.
• Constructed PtCu bimetallic nanozymes for the assay.
• Developed a paper-based immunoassay format.
• Utilized smartphone technology for result readout.
• Achieved rapid and accurate detection of CEA with high sensitivity.
• Demonstrated successful correlation between color change and CEA concentration.
• Portable device showed feasibility for early cancer screening.