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June 3, 2026Scientific ReportsOpen Access

Effect of Muller maneuver on upper airway characteristics and surrounding structures in patients with obstructive sleep apnea: a cone-beam computed tomography study

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Authors

SAS. Marjan ArianezhadYSYaser SafiMAMitra Ghazizadeh Ahsaie

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Overview

Prospective study assesses airway changes during the Muller maneuver in obstructive sleep apnea using imaging techniques, indicating clinical implications.

Key Points

  • This study evaluates how the Muller maneuver affects the upper airway and surrounding structures in patients with obstructive sleep apnea.
  • Performed cone-beam computed tomography scans during normal breathing and Muller maneuver in 18 patients.
  • Analyzed airway dimensions and soft tissue using linear, area, and volumetric measurements.
  • Statistical analyses included paired t-tests and two-way repeated-measures ANOVA.
  • Muller maneuver significantly decreased minimum anterior-posterior dimensions of nasopharynx by 6.41% (P = 0.048) and oropharynx by 38.81% (P = 0.006).
  • Significant airway volume reduction of 27.41% in oropharynx (P = 0.002) and 11.76% in upper airway (P = 0.048).
  • Notable changes in hyoid bone position and soft tissue length (P = 0.001, P = 0.016).

Cite This Study

Arianezhad et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc718dee9eb8c0dce7e6fhttps://doi.org/10.1038/s41598-026-55394-z
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  5. 5Comparison of Cortical Autonomic Network-Linked Sympathetic Excitation by Mueller Maneuvers and Breath-Holds in Subjects With and Without Obstructive Sleep Apnea2021 · 5 citations