Abnormal late atrial potentials were significantly more frequent in hypertensive patients with paroxysmal atrial fibrillation (86.9%) compared to those without (69.9%; P<0.001), informing a 14-point risk score.
Cohort (n=284)
Can a combined clinical and ECG scoring system stratify the risk of developing paroxysmal atrial fibrillation in hypertensive patients?
A proposed 14-point scoring system incorporating clinical and advanced ECG parameters may help identify hypertensive patients at high risk for developing paroxysmal atrial fibrillation.
Absolute Event Rate: 86.9% vs 69.9%
p-value: p=<0.001
Objective: AH patients with different disease duration and treatment with different CV risk were examined and followed longitudinally. The aim is risk stratification of patients, with regard to the developing atrial fibrillation (AF). Design and method: 284 patients (179 men, 105 women) were examined repeatedly: group 1 (n=133) with preserved LV function without paroxysmal AF, group 2 (n=130) with documented pAF, group 3 (n= 21) after radiofrequency ablation (RFA) for pAF/AFLA. All examined patients had sinus rhythm. NonECG data (clinical, laboratory data, echoCG, ABPM), ECG parameters (ECG, Holter ECG, VKG, high-resolution ECG, i.e. late ventricular potentials-LVPs. late atrial potentials-LAPs) were monitored. Results: Groups 1,2,3 did not differ significantly in BMI and monitored echoGG parameters. The differences between groups 1 and 2 was statistically significant in following parameters: non-dippers in ABPM, verified CHD, 3 or more combinations of drugs. In ECG parameters: abnormal LVPs and LAPs increased significantly between groups 1, 2 and 3. For LVPs: abnormal fQRSd (n, %) group 1: 61 (35.9), group 2: 71 (54.6), group 3: 17 (81.0), p60 years, (2) BMI >30, (3) DM, (4) HLP, (5) CHD, (6) post-CABG status, (7) non-dipper in ABPM. 7 ECG parameters in the score: (1) Holter ECG with ESVEA 30°, (5) abnormal fQRSd duration, (6) abnormal LVPs (3/3 or 2/3, (7) highly abnormal LAPs (abnormal nPd+abnormal fPd).
Filipová et al. (2026) conducted a cohort in Arterial hypertension (n=284). Clinical and ECG risk factors vs. Patients without paroxysmal atrial fibrillation was evaluated on Abnormal late atrial potentials (fPd) (p=<0.001). Abnormal late atrial potentials were significantly more frequent in hypertensive patients with paroxysmal atrial fibrillation (86.9%) compared to those without (69.9%; P<0.001), informing a 14-point risk score.
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