Key result
Obesity is associated with an increased risk of severe pneumonia, intubation, and mortality in patients with COVID-19, and may also negatively impact vaccine efficacy.
Obesity is a major risk factor for severe COVID-19 outcomes, including ICU admission and mechanical ventilation, highlighting the need for targeted management in this vulnerable population.
Obesity-associated risks may inform counseling in COVID-19; leaves open whether weight modification alters severity or vaccine response.
SARS-CoV-2, the agent of COVID-19 disease, mainly affects the respiratory tract. The severity of the disease ranges from subclinical infections to diseases with severe symptoms that require hospitalization. There are a number of comorbid factors that are important in treatment and follow-up. It has been found that most patients with severe disease have an underlying disease, advanced age, obesity, cardiovascular disease, liver disease, kidney disease or malignancy.
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Khaja et al. (2021) conducted a review in COVID-19 and Obesity. Obesity vs. Non-obese was evaluated. Obesity is associated with an increased risk of severe pneumonia, intubation, and mortality in patients with COVID-19, and may also negatively impact vaccine efficacy.
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