Why the study?
Does chronic dynamic exercise improve myocardial contractility and beta-adrenergic signal transduction in cardiomyopathic Syrian hamsters?
Population
14-week-old cardiomyopathic BIO 53.58 and normal F1B Syrian hamsters
Comparison
10 weeks of treadmill training vs 24-week-old BIO 53.58 and F1B untrained controls
Design
Preclinical
Follow-up
10 weeks
Authors
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Exercise may enhance Gs signaling and contractility in hamster cardiomyopathy; hypothesis-generating for human translation.
Does chronic dynamic exercise improve myocardial contractility and beta-adrenergic signal transduction in cardiomyopathic Syrian hamsters?
Chronic exercise training improves left ventricular contractility and the functional abnormality of Gs protein in cardiomyopathic Syrian hamsters.
Tomita et al. (1994) studied this question.
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