Why the study?
Cochlear dysfunction and otologic symptoms can arise from cardiovascular disorders, requiring an understanding of the association between cardiovascular disease risk factors and cochlear dysfunction.
Are major cardiovascular risk factors associated with sensorineural hearing loss?
Cross-Sectional (n=128)
Are major cardiovascular risk factors associated with sensorineural hearing loss?
Odds Ratio: 5.881 (95% CI 2.694–12.837)
p-value: p=<0.001
Major cardiovascular risk factors, including hypertension, dyslipidemia, and elevated BMI, are significantly associated with sensorineural hearing loss.
Background: Cochlear dysfunction can arise not only from various factors such as ear diseases but also from systemic disorders of the body. The occurrence of otologic symptoms such as hearing loss, dizziness, and tinnitus can be due to cardiovascular disorders. Therefore, current understandings in the field of the diagnosis and therapy of cardiovascular diseases (CVDs) should include, among others, evidence of otologic disorders. Objective: The aim of this study is to determine the association between risk factors for CVD and cochlear dysfunction. Methods: The cross-sectional study included 128 participants with major CVD risk factors who underwent auditory function examination (pure tone audiometry). Results: There were 52 women (40.6%) and 76 men (59.4%) in total. The mean age of the participants was 58 years (a range of 28–83 years). The mean age among participants with hearing loss was 60 (±10.88), whereas the mean age among participants that had normal hearing thresholds was 54 (±12.18). Sensorineural hearing loss (SNHL) was measured in 59% of participants, of most frequent mild degree hearing loss. The prevalence of SNHL was higher in participants with arterial hypertension (P < 0.001, OR = 5.881, 95% CI 2.694–12.837) and the most common among them was moderate degree hearing impairment (38%). There is also a statistically significant association of SNHL with dyslipidemia and elevated body mass index (P < 0.001, [OR]: 4.118, 95% [CI]: 1.873–9.053 and P< 0.001, [OR]: 1.517, 95% [CI]: 1.237–1.859 ) with moderate and profound hearing loss. Conclusion: Based on the data obtained, it seems that the presence of major cardiovascular risk factors was a significant predictor for cochlear dysfunction.
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Radivojevic et al. (2020) conducted a cross-sectional in Cochlear dysfunction (n=128). Arterial hypertension vs. Absence of arterial hypertension was evaluated on Sensorineural hearing loss (SNHL) (OR 5.881, 95% CI 2.694-12.837, p=<0.001).
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