Key result
Plasma adiponectin concentrations were positively correlated with insulin sensitivity measured by clamp (r=0.42, P<0.0001 in men) and OGTT, independent of sex and body fat percentage.
Why the study?
Does higher plasma adiponectin improve insulin sensitivity and lipid metabolism in nondiabetic individuals?
Population
Nondiabetic individuals
Design
Cross-sectional
Authors
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Supports adiponectin as insulin sensitivity biomarker; hypothesis-generating for causality in nondiabetics.
Observational
Does higher plasma adiponectin improve insulin sensitivity and lipid metabolism in nondiabetic individuals?
Effect estimate: r = 0.42 (men, clamp)
p-value: p=<0.0001
High plasma adiponectin concentrations independently predict increased insulin sensitivity and favorable lipid metabolism in nondiabetic individuals.
Tschritter et al. (2003) conducted an observational in Nondiabetic. Plasma adiponectin concentrations was evaluated on Insulin sensitivity measured by euglycemic-hyperinsulinemic clamp and estimated by oral glucose tolerance test (r = 0.42 (men, clamp), p=<0.0001). Plasma adiponectin concentrations were positively correlated with insulin sensitivity measured by clamp (r=0.42, P<0.0001 in men) and OGTT, independent of sex and body fat percentage.
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