Pediatric monomelic amyotrophy in vulnerable populations such as immigrant or adopted children is often consistent with prior poliomyelitis or polio-like virus myelitis.
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Supports polio history evaluation in immigrant children with monomelic amyotrophy; hypothesis-generating case series leaves broader validation open.
Pediatric monomelic amyotrophy may present a diagnostic challenge. This is particularly true for immigrant or adopted children who have little or no available medical history. We present clinical and electrophysiological data from 11 children with monomelic amyotrophy who had electrophysiological evidence of a unilateral or profoundly asymmetric motor neuronopathy. The cause of amyotrophy in each case is most consistent with prior: (1) wildtype poliovirus myelitis; (2) "polio-like" virus myelitis, or (3) vaccine associated paralytic poliomyelitis.
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McMillan et al. (2009) studied this question.
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